Big flavors, no fuss, and enough comfort to feed a hungry crowd—that’s the spirit behind John Wayne Beef Casserole. Named after the iconic Western film star, this dish is as rugged and satisfying as its namesake. It layers seasoned ground beef, vegetables, cheese, and a rich, creamy topping over a sturdy biscuit-style crust, creating a casserole that’s unapologetically filling and full of character.
This recipe became popular in community cookbooks and church suppers because it checks every box: easy to prepare, flexible with ingredients, and guaranteed to disappear fast.
What Makes John Wayne Beef Casserole Unique?
Unlike typical beef casseroles, this one stands out for its layered construction. Each component plays a role:
A golden biscuit base that soaks up flavor
Savory spiced beef and vegetables
A creamy, tangy cheese topping that seals everything together
The result is a bold, satisfying bake that eats like a full meal in every bite.
Ingredients You’ll Need
For the Crust
1 can refrigerated biscuit dough
2 tablespoons butter, melted
For the Beef Layer
1½ pounds ground beef
1 medium onion, chopped
1 green bell pepper, chopped
1 teaspoon salt
½ teaspoon black pepper
1 teaspoon chili powder
1 teaspoon paprika
For the Topping
1 cup sour cream
½ cup mayonnaise
1½ cups shredded cheddar cheese
1 cup shredded Monterey Jack cheese
1 can (10 oz) diced tomatoes with green chilies, drained